TLDR 2026-05-04
Meta humanoid robots 🤖, SpaceX costs leak 💰, open design 🧑🎨
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Science & Futuristic Technology
The company that built TikTok's algorithm is now designing drugs for diseases pharma called undruggable (10 minute read)
ByteDance has entered the AI drug discovery race. The company's drug discovery unit, Anew Labs, recently presented its first AI-designed therapy at a major immunology conference. Its work targeted a protein-protein interaction long thought to be undruggable. The unit has published a generative model that it claims can design functional molecules across all scales.
America's Electricity Gap (13 minute read)
Power access is incredibly important to tech companies' gamble on AI development. The US was always going to need more power investment to meet its next phase of economic growth and was already struggling to meet rising electricity demand well before the AI boom. The costs of the electricity gap are mounting as power becomes more important to the national economy. More of the US will have to permit the fast deployment of solar and batteries if they want to meet their own increasing electricity needs.
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Programming, Design & Data Science
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Try it freeOpen Design (GitHub Repo)
Open Design is an open-source alternative to Claude Design. It uses the same loop and artifact-first mental model with none of the lock-in. Open Design is local-first, web deployable, and supports several coding agents. It behaves like a senior designer with a working filesystem, a deterministic palette library, and a checklist culture.
Agent Skills (16 minute read)
AI coding agents are extremely capable, but they have no instinct for the parts of the job that don't show up in the diff. Agents will skip the senior-engineering work unless you make it impossible to skip. The job increasingly is to encode discipline as something agents can't talk themselves out of. Skills are one way to do that. The senior-engineer parts of the job are no longer optional, even when the engineer is a model.
OpenAI Wants to Go Public. First Sarah Friar Needs to Get It to Grow Up (14 minute read)
Sarah Friar was brought into OpenAI to give it the financial maturity needed to go public. Over the past few months, she has balanced the company's spending expectations and questioned the wisdom of spending even more money on data centers. It is up to Friar to pull off what could be one of the biggest IPOs ever. If she moves too slowly, OpenAI could fall behind and hit the market after Anthropic. Moving quickly risks stretching the business too far.
Sometimes smart planners lose to simple markets (11 minute read)
People think of the multi-agent future as analogous to our companies, just autonomous. However, AI agents are not like human agents, and the hub isn't just an equivalent of a human manager. If any of the subtasks are wrong, workers can be individually competent and the final answer will still be wrong. Markets work because people have local information that can't be easily shared.
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